Publications

138. "In Vitro and In Vivo Studies on a Mononuclear Ruthenium Complex Reveals It is a Highly Effective, Fast-Acting, Broad-Spectrum Antimicrobial in Physiologically Relevant Conditions" Adam M Varney, Kirsty L Smitten, Hannah M Southam, Simon D Fairbanks, Craig C Robertson, Jim A Thomas, Samantha McLean ACS Infectious Diseases, doi: 10.1021/acsinfecdis.4c00447

137. "Phenazine Cations as Anticancer Theranostics" Felicity F Noakes, Kirsty L Smitten, Laura EC Maple, Jorge Bernardino de la Serna, Craig C Robertson, Dylan Pritchard, Simon D Fairbanks, Julia A Weinstein, Carl GW Smythe, Jim A Thomas Journal of the American Chemical Society, 2024, 146, 12836-12849

136. "Iridium (III)-based minor groove binding complexes as DNA photocleavage agents" Stephen O Aderinto, Torsten John, Abdulmujeeb Onawole, Raphael Peter Galleh, Jim A Thomas Dalton Transactions, 2024, 53, 7282-7291

135. "From Chemotherapy to Phototherapy – Changing the Therapeutic Action of a Metallo-Intercalating RuII-ReI Luminescent System by Switching its Sub-Cellular Location" Hiwa K Saeed, Paul J Jarman, Sreejesh Sreedharan, Rachel Mowll, Alexander J Auty, Adrien AP Chauvet, Carl GW Smythe, Jorge Bernardino de la Serna, Jim A Thomas. Chemistry - A European Journal, 2023, 29, e202300617.

134. "Discovery of ruthenium (II) metallocompound and olaparib synergy for cancer combination therapy." Nur Aininie Yusoh, Paul R Tiley, Steffan D James, Siti Norain Harun, Jim A Thomas, Norazalina Saad, Ling-Wei Hii, Suet Lin Chia, Martin R Gill, Haslina Ahmad Journal of Medicinal Chemistry, 2023, 66, 6922-6937.

133. "2, 2′: 4, 4′′: 4′, 4′′′-Quaterpyridine: synthesis, crystal-structure description, and Hirshfeld surface analysis." Stephen O Aderinto, Jim A Thomas, Craig C Robertson Structure Reports, 2023, 79, 356-360.

132. "Clearing an ESKAPE pathogen in a model organism; a polypyridyl ruthenium (II) complex theranostic that treats a resistant Acinetobacter baumannii infection in Galleria mellonella" Kirsty Smitten, Hannah M Southam, Simon Fairbanks, Arthur Graf, Adrien Chauvet, Jim A Thomas, Chemistry - A European Journal, 2023, 29, e202203555

131. "Selectively inhibiting malignant melanoma migration and invasion in an engineered skin model using actin-targeting dinuclear Ru II-complexes." Ahtasham Raza, Stuart A Archer, Jim A Thomas, Sheila MacNeil, John W Haycock RSC Medicinal Chemistry, 2023, 14, 65-73

130. "Nanoparticles for super-resolution microscopy: intracellular delivery and molecular targeting." Sumit Kumar Pramanik, Sreejesh Sreedharan, Rajeshwari Tiwari, Sourav Dutta, Noufal Kandoth, Surajit Barman, Stephen O Aderinto, Samit Chattopadhyay, Amitava Das, Jim A Thomas Chemical Society Reviews, 2022, 51, 9882-9916.

129. "A dinuclear osmium(II) complex near-infrared nanoscopy probe for nuclear DNA.”
Fabian Dröge, Felicity Noakes, Stuart A. Archer Sreejesh Sreedharan, Ahtasham Raza, Craig C Robertson, Sheila MacNeil, John W. Haycock, Heather Carson, Anthony J.H.M. Meijer, Carl G. W. Smythe, Jorge Bernardino de la Serna, Benjamin Dietzek-Ivanšić and Jim A Thomas
Journal of the American Chemical Society, 2022, 143, 20442-20453

128. "Being positive is not everything – experimental and computational studies on the selectivity of a self-assembled, multiple redox-state, receptor that binds anions with up to picomolar affinities” Ahmed Zubi, Hawazin A Alnafisah, Simon Turega, Igor Marques, José RB Gomes, Jim A Thomas,and Vítor Félix
Chemistry—A European Journal, 2022, 22, e202102465

127. “A Minimal Load-and-lock RuII Luminescent DNA Probe”  Matthew D Newton, Simon D Fairbanks, Jim A Thomas, and David S Reuda
Angewandte Chemie International Edition, 2021, 60, 20952–20959

126. “Amyloid binding and beyond: a new approach for Alzheimer's disease drug discovery targeting Aβo–PrPC binding and downstream pathways” James D. Grayson, Matthew P. Baumgartner, Cleide Dos Santos Souza, Samuel J. Dawes, Imane Ghafir El Idrissi, Jennifer C. Louth, Sasha Stimpson, Emma Mead, Charlotte Dunbar, Joanna Wolak, Gary Sharman, David Evans, Anastasia Zhuravleva, Margarita Segovia Roldan, Nicola Antonio Colabufo, Ke Ning, Claire Garwood, James A Thomas, Benjamin M Partridge, Antonio de la Vega de Leon, Valerie J. Gillet, Amélia P Rauter, and Beining Chen
Chemical Science, 2021, 12, 3768-3785.

125. ”Transcriptomic Analysis of the Activity and Mechanism of Action of a Ruthenium(II)- Based Antimicrobial That Induces Minimal Evolution of Pathogen Resistance Adam M Varney, Kirsty L Smitten, Jim A Thomas, Samantha McLean
ACS Pharmacology and Translational Science. 2021, 4, 168-178.

124. “Nanocarriers used as probes for super-resolution microscopy” Sreejesh Sreedharan, Rajeshwari Tiwari, Deepak Tyde, Stephen O Aderinto, Sumit Kumar Pramanik, Amitava Das, James A Thomas
Materials Chemistry Frontiers, 2021, 5, 1268-1282.

123. “An 111In-labelled bis-ruthenium(II) dipyridophenazine theranostic complex: Mismatch DNA binding and selective radiotoxicity towards MMR-deficient cancer cells” Martin R Gill, Michael G Walker, Sarah Able, Ole Tietz, Abirami Lakshminarayanan, Rachel Anderson, Rod Chalk, Afaf Helmy El-Sagheer, Tom Brown, Jim A Thomas, Katherine Valli
Chemical Science, 2020, 11, 8936-8944.

122. “Triazole-based Osmium(II) Complexes Displaying Red/Near_IT Luminescence: antimicrobial activity and Super-Resolution Imaging” Kirsty Smitten, Paul A Scattergood, Charlotte Kiker, Jim A Thomas, and Paul Elliot
Chemical Science, 2020, 11, 8928-8935.

121. “Mononuclear Ruthenium(II) Complexes that Function as Broad-spectrum Anitmicrobials in Therapeutically Resistant Pathogens through Interaction with DNA” Kirsty Smitten, Eleanor J Thick, Hannah M Southam, Jorge Bernardino de la Serna, Simon J Foster, and Jim A Thomas
Chemical Science, 2020, 11, 8828-8838.

120. “Mitochondriotopic Lanthanide Nanorods: Implications for Multimodal Imaging” Harwinder Singh, Sreejesh Sreedharan, Esteban Oyarzabel, Tufan Singha Mahapatra Nicola Green, Shih Yen-Yu Iam, Manasmita Das, Jim A Thomas, Sumit Kumar Pamanik, and Amitava Das
Chemical Communications, 2020, 56, 7945-7948.

119. “Photoactive metal complexes that bind DNA and other biomolecules as cell probes Therapeutics, and theranostics” Hiwa K. Saeed, Sreejesh Sreedharan, and Jim A Thomas
Chemical Communications, 2020, 56, 1464-1480.

118. “A dinuclear ruthenium(II) complex excited by near-infrared light through two-photon absorption induces phototoxicity deep within hypoxic regions of melanoma cancer spheroids” Ahtasham Raza, Stuart A Archer, Simon D Fairbanks, Kirsty L Smitten, Stanley W Botchway, Jim A Thomas, Sheila MacNeil, John W. Haycock
Journal of the American Chemical Society, 2020,  142, 4639-4647.

117. “Making the right link to theranostics: the photophysical and biological properties of dinuclear RuII-ReI dppz complexes depend on their tether” Hiwa K. Saeed, Sreejesh Sreedharan, Paul J. Jarman, Stuart A. Archer, Simon D. Fairbanks, Simon P Foxon, Alexander J Auty, Dimitri Chekulaev, Theo Keane, Anthony JHM Meijer, Julia A Weinstein, Carl GW Smythe, Jorge Bernardino de la Serna, Jim A Thomas
Journal of the American Chemical Society, 2020,  142, 1101-1111.

116. “Ruthenium based antimicrobial theranostics – using nanoscopy to identify therapeutic targets and resistance mechanisms in Staphylococcus aureus” Kirsty Smitten, Simon D Fairbanks, Craig C Robertson, Jorge Bernardino de la Serna, Simon J. Foster, and Jim A Thomas
Chem Sci, 2020,  11, 70-79.

115. “Using Nanoscopy to Probe the Biological Activity of Antimicrobial Leads that Display Potent Activity Against Pathogenic, Multi-drug Resistant, Gram-negative Bacteria” Kirsty Smitten, Hannah M Southam, Jorge Bernardino de la Serna, Martin R Gill, Paul J Jarman,  Carl G W Smythe, Robert K Poole, and Jim A Thomas
ACS Nano, 2019, 13, 5133-5146.

114. “Structural investigation into the threading intercalation of a chiral dinuclear ruthenium (II) polypyridyl complex through a B-DNA oligonucleotide” Simon D Fairbanks, Craig C Robertson, F Richard Keene, Jim A Thomas, and  Mike P Williamson
Journal of the American Chemical Society, 2019, 141, 4644–4652.

113. “A dinuclear ruthenium(II) phototherapeutic that targets duplex and quadruplex DNA” Stuart A. Archer, Ahtasham Raza, Fabian Dröege,  Craig Robertson, Alexander J Auty, Dimitri M Chekulaev, Julia A Weinstein, Theo Keane, Anthony JHM Meijer, John W Haycock, Sheila MacNeil, James A Thomas
Chemical Science, 2019, 10, 3502-3513.

112. “Exploring the cytotoxicity, uptake, cellular response, and proteomics of mono- and dinuclear DNA light-switch complexes”  Paul Jarman, Felicity Noakes,  Simon Fairbanks, Kirsty Smitten, Isabel Griffiths, Hiwa Saeed, Jim Thomas, Carl Smythe
Journal of the American Chemical Society, 2019, 141, 925–2937.

111. “Two photon excitable graphene quantum dots for structured illumination microscopy and imaging application: lysosome specificity and tissue-dependent imaging” Harwinder Singh, Sreejesh Sreedharan, Karishma Tiwari, Nicola H. Green, Carl Smythe, Sumit Kumar Pramanik, Jim. A. Thomas and Amitava Das
Chemical Communications, 2019, 55, 521-524

110. “A Fluorescent Chemodosimeter for Organelle-Specific Imaging of 2 Nucleoside Polyphosphate Dynamics in Living Cells” Harwinder Singh, Sreejesh Sreedharan, Rajeswari Tiwari, Christa Walther, Carl Smythe, Sumit Kumar Pramanik, Jim A Thomas, and Amitava Das
Crystal Growth and Design, 2018, 18, 7199–7206.

109. “Turning intercalators into groove binders: synthesis, photophysics and DNA binding properties of tetracationic mononuclear Ruthenium(II)-based chromophore-quencher complexes” Hanan S Derrat, Craig C Robertson, Anthony JHM Meijer and Jim A Thomas
Dalton Transactions, 2018,47, 12300–12307.

108. “Mitochondria Targeting Non-isocyanate-based Polyurethane Nanocapsules for Enzyme-Triggered Drug Release” Sumit Pramanik, Sreejesh Sreedharan, Harwinder  Singh, Mohsina Khan, Karishma Tiwari, Anjali Shiras, Carl Smythe, Jim Thomas, Amitava Das
Bioconjugate Chemistry, 2018, 29, 3532-3543.

107. “111In-labelled polymeric nanoparticles incorporating a ruthenium-based radiosensitizer for EGFR-targeted combination therapy in oesophageal cancer cells” Martin R Gill, Jyothi U Menon, Paul J Jarman, Joshua Owen, Irini Skaripa-Koukelli, Sarah Able, Jim A Thomas, Robert Carlisle, Katherine A Vallis
Nanoscale, 2018, 10, 10596-10606.

106. “A Polysulfide-Triggered Fluorescent Indicator Suitable for Super-Resolution Microscopy and Application in Imaging” Anila Hoskere A, Sreejesh Sreedharan, Firoj Ali, Carl G. Smythe, Jim A. Thomas and Amitava Das
Chemical Communications, 2018, 54, 3735-3738.

105. “Mitochondria-localising DNA-binding  biscyclometalated phenyltriazole iridium(III) dipyridophenazene complexes: syntheses and cellular imaging properties” Sreejesh Sreedharan, Alessandro Sinopoli, Paul Jarman, Darren Robinson, Christopher Clemmet, Paul A Scttergood,  Craig R. Rice, Carl G W Smythe, James A. Thomas, and Paul I.P Elliott
Dalton Transactions, 2018, 47, 4931–4940.

104. “Tracking HOCl Concentrations Across Cellular Organelles in Real time using a Super resolution Microscopy Probe” Firoj Ali, Sunil Aute, Sreejesh Sreedharan, Anila H A, Hiwa K Saeed, Carl G Smythe, Jim A Thomas, and Amitava Das
Chemical Communications, 2018, 54, 1849-1852.

103. “A three-in-one-bullet for oesophageal cancer: Replication fork collapse, spindle attachment failure and enhanced radiosensitivity generated by a ruthenium(II) metallo-intercalator” Martin R Gill, Paul J. Jarman, Swagata Halder, Michael G Walker, Hiwa K Saeed, Jim A. Thomas, Carl Smythe, Kristijan Ramadan, Katherine A. Vallis
Chemical Science, 2018, 9, 841–849.

102. “Targeting cellular DNA with Luminescent Ruthenium (II) Polypyridyl Complexes” Martin R Gill, and Jim A Thomas
Ruthenium Complexes: Photochemical and Biomedical Applications (Wiley‐VCH Verlag GmbH & Co) 2018, 221–238.

101. “Imaging cellular trafficking processes in real time using lysosome targeted up-conversion nanoparticles.” Sumit Kumar Pramanik, Sreejesh Sreedharan, Harwinder Singh, Carl Smythe, Jim A Thomas, and Amitava Das
Chemical Communications, 2017, 53, 12672–12675.

100. “A super Resolution Probe to Monitor HNO Levels in the Endoplasmic Reticulum of Cells”Firoj Ali,  Sreejesh  Sreedharan, Anila Ashoka, Hiwa Saeed, Carl; Smythe, Jim A Thomas, Amitava Das
Analytical Chemistry, 2017, 89 , 12087–12093.

99. “Multimodal super-resolution optical microscopy using a transition metal-based probe provides unprecedented capabilities for imaging both nuclear chromatin and mitochondria” Sreejesh Sreedharan, Martin R Gill, Esther Garcia, Hiwa K Saeed, Darren Robinson, Aisling Byrne, Ashley Cadby, Tia E Keyes, Carl Smythe, Patrina Pellett, Jorge Bernardino de la Serna, and Jim A Thomas
Journal of the American Chemical Society, 2017 139,15907-15913.

98. “Homo- and heteroleptic phototoxic dinuclear metallo-intercalators based on RuII(dppn)intercalating moieties: synthesis, optical and biological studies” Hiwa K. Saeed, Paul J.Jarman, Stuart Archer, Sreejesh Sreedharan, Ibrahim Q Saeed, Luke K McKenzie, Julia A Weinstein, Niklaas J Buurma, Carl G. W. Smythe, and Jim A Thomas
Angewandte Chemie International Edition, 2017, 56, 12628-12633.

97. “Synthesis, crystal structure and magnetic properties of [Co(bpcam)2]ClO4·dmso·H2O, [Co(bpcam)2]2[Co(NCS)4]·dmso·H2O and [Ni(bpcam)2]·H2O [Hbpcam = bis(2-pyrimidylcarbonyl)amide]” Renato Rabelo, Ana K. Valdo, Craig Robertson, Jim A. Thomas, Humberto O. Stumpf, Felipe T. Martins, Emerson F Pedroso, Miguel Julve, Francesc Llore and Danielle Cangussu
New Journal of Chemistry, 2017, 41, 6911.

96. “Photo-Induced Cytotoxicity and Anti-Metastatic Activity of Ruthenium(II)-Polypyridyl Complexes Functionalized with Tyrosine or Tryptophan” Vadde Ramu, Sunil Aute, Nandaraj Taye, Michael G. Walker, Devaraj Mogare, Jim A Thomas, Samit Chattopadhyay, and Amitava Das
Dalton Transactions, 2017, 46, 6634 - 6644.

95. “A ratiometric sensor for DNA based on a dual emission Ru(dppz) light-switch complex” Michael G. Walker, Vadde Ramu, Anthony JHM Meijer, Amitava Das and Jim A Thomas
Dalton Transactions, 2017, 46, 6079 - 6086.

94. “The structure of linkers affects the DNA binding properties of tethered dinuclear ruthenium (II) metallo-intercalators” Hiwa K. Saeed, Ibrahim Q Saeed, Niklaas J Buurma, and Jim A Thomas
Chemistry—A European Journal, 2017, 23, 5467–5477. ("Hot paper" and inside front cover).

93. “A self-assembled metallomacrocycle singlet oxygen sensitizer for photodynamic therapy” Michael G. Walker, Paul  J. Jarman, Martin R. Gill, Xiaohe Tian, Haslina Ahmad, Pattubala AN Reddy, Luke McKenzie, Julia A Weinstein, Anthony JR Meijer, Giuseppe Battaglia, Carl GW Smythe, and Jim A Thomas
Chemistry—A European Journal, 2016, 22, 5996–6000.

92. “Terminal PEGylated DNA–Gold Nanoparticle Conjugates Offering High Resistance to Nuclease Degradation and Efficient Intracellular Delivery of DNA Binding Agents” Lei Song, Yuan Guo, Deborah Roebuck, Chun Chen, Min Yang, Zhongqiang Yang, Sreejesh Sreedharan, Caroline Glover, Jim A Thomas, Dongsheng Liu, Shengrong Guo, Rongjun Chen, and Dejian Zhou, ACS ACS Applied Materials and Interfaces, 2015, 7, 18707−18716.

91. “Serum albumin binding inhibits nuclear uptake of luminescent metal complex-based DNA imaging probes” Ashley Wragg, Martin R. Gill, Luke McKenzie, Caroline Glover, Rachel Mowll, Julia A. Weinstein, Xiaodi Su, Carl Smythe and Jim A. Thomas
Chemistry—A European Journal, 2015, 21, 11865–11871.

90. “Optical imaging probes for biomolecules: An introductory perspective” Jim A Thomas
Chemical Society Reviews, 2015, 44, 4494–4500.

89. “A cytostatic ruthenium(II)-platinum(II) bis(terpyridyl) anticancer complex that blocks entry into S phase by up-regulating p27KIP1” Vadde Ramu, Martin R. Gill, Paul Jarman, Jim A. Thomas, Amitava Das, Carl Smythe
Chemistry—A European Journal, 2015, 21, 9185–9197.

88. “Tuning the Excited State of Water-Soluble IrIII-Based DNA Intercalators that are Isostructural with [RuII(NN)2(dppz)] Light-Switch Complexes” Sasha Stimpson, Dan R Jenkinson, Andrew Sadler, Mark Latham, Ashley Wragg, Anthony JHM Meijer, Jim A Thomas
Angewandte Chemie International Edition, 2015, 54, 3000–3003.

87. “Modulating the electron-transfer properties of a mixed-valence system through host–guest chemistry” Ahmed Zubi, Ashley Wragg, Simon Turega, Harry Adams, Paulo J Costa, Vítor Félix, Jim A Thomas
Chemical Science, 2015, 6, 1334–1340.

86. “Tuning the Cellular Uptake Properties of Luminescent Heterobimetallic Iridium(III)–Ruthenium(II) DNA Imaging Probes”  Ashley Wragg, Martin R Gill, David Turton, Harry Adams, Thomas M Roseveare, Carl Smythe, Xiaodi Su and Jim Thomas
Chemistry—A European Journal, 2014, 20, 3089-3096.

85. “Dinuclear osmium(II) probes for high-resolution visualisation of cellular DNA structure using electron microscopy” Ashley Wragg, Martin R Gill, Christopher J Hill, Xiaodi Su, Anthony JHM Meijer, Carl Smythe, Jim A Thomas
Chemical Communications, 2014, 50, 14494-14497 (front cover).

84. “Dinuclear Ruthenium(II) Complexes as Two-Photon, Time-Resolved Emission Microscopy Probes for Cellular DNA” Elizabeth Baggaley, Martin R Gill, Nicola H Green, David Turton, Igor V Sazanovich, Stanley W Botchway, Carl Smythe, John W Haycock, Julia A Weinstein, Jim A Thomas
Angewandte Chemie International Edition, 2014, 53, 3367-71 (front cover; selected as a F1000Prime paper).

83. “From Intercalation to Groove Binding: Switching the DNA-Binding Mode of Isostructural Transition-Metal Complexes” Haslina Ahmad, Ashley Wragg, Will Cullen, Claire Wombwell, Anthony JHM Meijer, Jim A Thomas
Chemistry—A European Journal, 2014, 20, 3089-3096.

82. “Using ancillary ligands to tune the DNA binding properties of self-assembled luminescent metallomacrocycles.” Haslina Ahmad, Dipesh Ghosh, Jim A Thomas
Chemical Communications, 2014, 50, 3859-3861.

81. “Targeting the endoplasmic reticulum with a membrane-interactive luminescent ruthenium(II) polypyridyl complex” Martin R Gill, Denis Ceccin, Michael G Walker, Raminder S Mulla, Guiseppe Battaglia, Carl Smythe, Jim A Thomas
Chemical Science 2013, 4,4512-4519.

80. “Structural studies on dinuclear ruthenium(II) complexes that bind diastereoselectively to an anti-parallel folded human telomer sequence,” Tom Wilson, Paulo J Costa, Vitor Felix, Mike P Williamson, Jim A Thomas
Journal of Medicinal Chemistry, 2013, 56, 8674–8683.

79. “Tuning electronic interactions in mixed valence ruthenium systems incorporating thiacrown ligands”, Jim A Thomas
Coordination Chemistry Reviews, 2013, 257, 1555–1563.

78. “A Self-Assembled Luminescent Host That Selectively Senses ATP in Water”, Haslina Ahmad, Benedict W Hazel,  Anthony JHM Meijer, Jim A Thomas,  and Karl A Wilkinson
Chemistry—A European Journal, 2013, 19, 5081-5087.

77. “Temperature-Switched Binding of a Ru-II(dppz)/DNA Light-Switch Complex”, Michael G. Walker, Veronica Gonzalez, Elena Chekmenova and Jim A Thomas
Angewandte Chemie International Edition, 2012, 51, 12107-12110.

76. “Ruthenium(II) Thiacrown Complexes Incorporating Noninnocent Redox Active Ligands: Synthesis, Electrochemical Properties, and Theoretical Studies”, James D Ingram, Paulo J Costa, Harry Adams, Mike D Ward, V Felix,and Jim A Thomas
Inorganic Chemistry, 2012, 51, 10483-10494.

75. “Ruthenium(II) polypyridyl complexes and DNA-from structural probes to cellular imaging and therapeutics”, Martin R Gill, and Jim A Thomas
Chemical Society Reviews, 2012, 41, 3179-3192.

74. “Synthesis, Characterization, and DNA Binding Properties of Ruthenium(II) Complexes Containing the Redox Active Ligand Benzo[i]dipyrido[3,2-a:2 ',3 '-c]phenazine-11,16-quinone”, Simon P Foxon, Charlotte Green, Michael G. Walker, Ashley Wragg, Harry Adams, Julia A Weinstein, Simon C Parker, Anthony JHM Meijer, and Jim A Thomas
Inorganic Chemistry, 2012, 51, 463-471.

73. “Metal-ion directed self-assembly of sensors for ions, molecules and biomolecules”, Jim A Thomas
Dalton Transactions, 2011, 40, 12005–12016.

72. “Tuning the excited state of photoactive building blocks for for metal-templated self-assembly” Haslina Ahmad, Anthony J. H. M. Meijer, and Jim A Thomas
Chemistry – An Asian Journal, 2011, 9, 2339–2351.

71. “A water-soluble amino derivatives of free-base dppz – synthesis and DNA binding studies” Tim Phillps, Itshamul Haq, and Jim A Thomas
Organic and Biomolecular Chemistry, 2011, 9, 3462–3470.

70. “Ruthenium(II) metallo-intercalators: DNA imaging and cytotoxicity” Martin R Gill, Hanan Derrat, Carl GW Smythe, Giuseppe Battaglia, and Jim A Thomas
ChemBioChem, 2011, 12, 877–880.

69. “Live Cell Luminescence Imaging As a Function of Delivery Mechanism” Xiaohe Tian, Martin R Gill, Irene Cant, Jim A Thomas, and Giuseppe Battaglia
ChemBioChem, 2011,12, 548–551.

68. “Photoactive RuII–Polypyridyl Complexes that Display Sequence Selectivity and High-Affinity Binding to Duplex DNA through Groove Binding"  Amrita Ghosh, Priyadip Das, Martin R Gill, Prasenjit Kar, Michael G Walker, Jim A Thomas, and Amitava Das, Chemistry - A European Journal, 2011, 17, 2089–2098. (inside cover).

67. “Differentiating quadruplexes: binding preferences of a luminescent dinuclear ruthenium(II) complex with four-stranded DNA structures.”  T Wilson, MP Williamson and Jim A Thomas
Organic and Biomolecular Chemistry, 2010, 8, 2617-2621. 

66. “A Back-to-Back Ligand with Dipyrazolylpyridine and Dipicolylamine Metal-Binding Domains”  Clare Tovee, Jim A Thomas and Malcolm A Halcrow
European Journal of Inorganic Chemistry, 2010, 1007-1012 (front cover).

65. “Structure of the complex of [Ru(tpm)(dppz)py]2+ with a B-DNA oligonucleotide - a single-substituent binding switch for a metallo-intercalator.” Phil Waywell, Veronica Gonzalez, Martin R. Gill, Harry Adams, Anthony J. H. M. Meijer, Mike P Williamson, Jim A Thomas
Chemistry – A European Journal, 2010, 16, 2407-2417 (inside cover).

64. “Co-crystallising Two Functional Complex Molecules in a Terpyridine Embrace Lattice” Clare A Tovee, Colin A Kilner, Jim A Thomas and Malcolm A Halcrow, Jim A Thomas
CrystEngComm, 2009, 11, 2069-2077.

63. “DNA binding and cleavage properties of a newly synthesized Ru(II)-polypyridyl complex” With Amrita Ghosh, Amit Mandoli, D. Krishna. Kumar, Narendra S. Yadav, Tamal Ghosh, Bhavanath Jha, Jim A Thomas, Amitava Das
Dalton Transactions, 2009, 9312-9321

62. “A Ruthenium(II) Polypyridyl Complex for Direct Imaging of DNA Structure in Living Cells.”  Martin R. Gill, Jorge Garcia-Lara, Simon J. Foster, Carl Smythe, Guiseppe Battaglia, Jim A Thomas
Nature Chemistry, 1, 662-667

61. “Photophysical properties and singlet oxygen production by Ruthenium(II) Complexes of Benzo[i]dipyrido[3,2-a:2’,3’-c]phenazine: a spectroscopic and TD DFT study,” Simon P. Foxon, Mike Walker, Mohammed A. H. Alamiry, Anthony J. H. M. Meijer, Igor V. Sazanovich, Julia A. Weinstein, Jim A Thomas
The Journal of Physical Chemistry A, 2009, 113, 12754-12762

60. “Kinetically locked luminescent metallomacrocycles as duplex DNA binding substrates,” Dipesh Ghosh, Haslina Ahmad, Jim A Thomas
Chemical Communications, 2009, 2947–2949.

59. “A hydrophobic haven for Base Pairs,” Jim A Thomas
Nature Chemistry, 2009, 1, 25–26.

58. “Mixed Valence Creutz-Taube ion Analogues Incorporating Thiacrowns: Synthesis, Structure, Physical Properties, and Computational Studies,”  Harry Adams, Paulo J Costa, Mike Newell, Steven J Vickers, Michael D Ward, Vítor Félix, Jim A Thomas
Inorganic Chemistry, 2008, 47, 11633 - 11643.

57. “Self-assembly of Electroactive Thiacrown Ruthenium(II) Complexes into Hydrogen-bonded Chain and Tape Networks,” Naz Shan, Samuel M. Hawxwell, Harry Adams, Lee Brammer, Jim A. Thomas
Inorganic Chemistry, 2008, 47, 11551 - 11560. 

56. “Syntheses, crystal structures and magnetic properties of tricyanomethanide-containing bis(2-pyrimidylcarbonyl)amidate copper(II) complexes,” Consuelo Yuste, Danielle Cangussu de Castro Gomes, Harry Adams, Jim A Thomas, Francesc Lloret, and Miguel Julve
Polyhedron, 2008, 27, 2577-2584.

55. “A dinuclear ruthenium(II) complex that functions as a label-free colorimetric sensor for DNA,” V Gonzalez, T Wilson, I Kurihara, A Imai, JA Thomas, J Otsuki
Chemical Communications, 2008, 168–170.

54. “Syntheses, crystal structures and magnetic properties of mono- and polynuclear bis(2-arylcarbonyl)amidatecopper(II) complexes,” D. C. de Castro Gomes,  LM Toma, HO Stumpf, H Adams, F Lloret, JA Thomas, M Julve
Polyhedron, 2008, 27,559 – 573.

53. “Nanosecond Transient Absorption Studies of Ru(II) complexes with Tris(1-pyrazolyl)methane Unit and an intercalating benzo[i]dipyrido[3,2-a:2',3'-c]phenazine (dppn) ligand,” MAH Alamiry, S Foxon, JA Thomas, JA Weinstein
CLF Annual Report, 2007, 149–151.

52. “Zwitterionic 2-(4-Pyridyl)malondialdehyde Sesquihydrate Forms a Helical, Three-Dimensional Hydrogen-Bonded Lattice,” C. A Tovee, CA Kilner, JA Thomas, M Halcrow
CrystEngComm, 2007, 9, 361–63.

51. “A Multifuctional Light-Switch: DNA Binding and Cleavage Properties of a Heterobimetallic Ruthenium-Rhenium Dipyridophenazine Complex,” SP Foxon, M Towrie, AW Parker, M Webb, JA Thomas
Angewandte Chemie International Edition, 2007, 46, 3686–3688.

50. “Locking self-assembly: strategies and outcomes,” JA Thomas
Chemical Society Reviews, 2007, 36, 856–868.

49. “Tuning Electrochemical and Photophysical Properties of DNA Metallo-intercalators Containing the Ruthenium(II) tris(1-pyrazolyl)methane Unit,” S. P. Foxon, C Metcalfe, H Adams, M Webb, JA Thomas
Inorganic Chemistry, 2007, 46, 409–416.

48. “Photophysical studies on novel DNA light switches," SP Foxon, JA Thomas
CLF Annual Report, 2006, 162-64

47. “Functional Molecular Materials,” JA Thomas
Angewandte Chemie International Edition, 2006, 45, 4396 - 4398.

46. “Studies on the Interaction of Extended Terpyridyl and Triazine Metal Complexes with DNA,” C Metcalfe, C Rajput, JA Thomas,
Journal of Inorganic Biochemistry, 2006, 100, 1314 -1319 .

45. “Dinuclear RuII complexes that display high affinity binding to duplex and quadruplex DNA,” C Rajput, L Swanson, R Rutkaite, I Haq, JA Thomas
Chemistry – A European Journal, 2006, 12, 4611–4619.

44. “Kinetically locked, trinuclear RuII metallo-macrocycles – synthesis and electrochemical properties,” N Shan, S Vickers, H Adams, MD Ward, JA Thomas
Dalton Transactions, 2006, 2900–2906.

43. “Structure and Properties of Dinuclear [RuII([n]aneS4) Complexes of 3,6-bis(2-pyridyl)-1,2,4,5- tetrazine,” M Newell, JD Ingram, TL Easun, SJ Vickers, MD Ward, JA Thomas
Inorganic Chemistry, 2006, 45, 821–827.

42. "Self-assembled kinetically locked RuII-based metallomacrocyles: physical, structural, and modeling studies." P de Wolf, P Waywell, M Hanson, SL Heath, AJHM Meijer, SJ Teat, JA Thomas
Chemistry – A European Journal, 2006, 12, 2188–2195.(front cover)

41. “Ruthenium(II) thiacrown complexes as hydrogen-transfer reduction catalysts,” N Shan, H Adams, JA Thomas
Inorganica Chimica Acta, 2006, 359, 759–765.

40. “Electrochemical properties of dinuclear [Ru([n]-ane-S4] complexes of 2,3-bis(2-pyridyl)pyrazine,” M Newell, JA Thomas
Dalton Transactions, 2006, 705–709.

39. “Tuning DNA binding affinities and photoredox properties of water-soluble organic dppz analogues,” T Phillips, C Rajput, L Twyman, I Haq
Chemical Communications, 2005, 4327-29.

38. “Design of single cyanide-bridged tetranuclear bimetallic rectangles exhibiting ferromagnetic coupling,” LM Toma, R Lescouëzec, D Cangussu, R Llusar, J Mata, S Spey, JA Thomas, F Lloret, M Julve
Inorganic Chemistry Communications, 2005, 8, 382–385.

37. “Oxalate, squarate and croconate complexes with bis(2-pyrimidylcarbonyl)amidate copper(II): synthesis, crystal structures and magnetic properties,” D. Cangussu, H. O. Stumpf, H. Adams, J. A. Thomas, F. Lloret, M. Julve
Inorganica Chimica Acta, 2005, 358, 2292–2302.

36. “Ru(II) Complexes Incorporating Tetrathia-macrocycles: Synthesis and Conformational Analysis,” H Adams, AM Amado, V Félix, BE Mann, J Antelo-Martinez, M Newell, PJA Ribeiro-Claro, SE Spey, JA Thomas
Chemistry – A European Journal, 2005, 11, 2031 - 2046. (selected as a issue highlight)

35. “Copper(II) assisted hydrolysis of 2,4,6-Tris(2-pyrimidyl)-1,3,5-triazine (tpymt). Syntheses, crystal structures and magnetic properties of [Cu(bpcam)(H2O)2]ClO4.3H2O, [Cu(bpcam)(H2O)2] [Cu(bpcam)(H2O)(SO4)].2H2O and [Cu2(bpcam)2(H2O)2(SO4)].H2O [bpcam = bis(2-pyrimidylcarbonyl)amidate)],” D Cangussu de Castro Gomes, HO Stumpf, F Lloret, M Julve, V Gonzalez, Harry Adams, JA Thomas
Inorganica Chimica Acta, 2005, 358, 1113–1124.

34.  “A convenient synthetic route to half-sandwich rhodium(III) complexes of the tripodal ligand (tris(3,5-dimethylpyrazolyl)methane,” V Gonzalez, Harry Adams, JA Thomas
Journal of the Chemical Society, Dalton Trans., 2005, 110–115.

33. “DNA binding of an organic dppz-based intercalator.” T Phillips, I Haq, AJHM Meijer, H Adams, I Soutar, L Swanson, MJ Sykes, JA Thomas
Biochemistry, 2004, 43, 13657–65.

32. “Switchable electron transfer processes in a mixed valence, kinetically locked, trinuclear RuII metallo-macrocycle,” N Shan, S Vickers, H Adams, MD Ward, JA Thomas
Angewandte Chemie International Edition, 2004, 43, 3398-41.

31.  “Hydrogen bonding thiacrown complexes-the structure [RuCl([9]-ane-S3)(L)2][PF6] (where L = nicotinamide),” H Adams, N Shan, JA Thomas
Acta Crystallographica Section E, 2004, 60, m662.

30. “Synthesis and structure of rhodium complexes containing extended terpyridyl ligands,”  J Paul, S Spey, H Adams, J Thomas
Inorganica Chimica Acta, 2004, 354, 2827–2832.

29. “A facile route to bimetallic ruthenium dipyridophenazine complexes,” C Metcalfe, I Haq, JA Thomas
Inorganic Chemistry, 2004, 43, 317–323.

28. “Self-Assembly: Definition and Kinetic and Thermodynamic Considerations,” JA Thomas
Encyclopedia of Supramolecular Chemistry, J. Steed and J. Atwood (Eds) (Marcel Dekker, New York, 2004)

27. “New 2,2’:4,4’’:4’,4’’’-quaterpyridyl transition metal complexes,” P de Wolf, SL Heath, JA Thomas
Inorganica Chimica Acta, 2003, 355C, 280–285.

26. “Kinetically inert transition metal complexes that reversibly bind to DNA,” C Metcalfe, JA Thomas
Chemical Society Reviews, 2003, 32, 214–224. (featured on cover)

25. “A ruthenium dipyridylpyrazine complex that binds preferentially to GC sequences.” C Metcalfe, H Adams, I Haq, JA Thomas
Chemical Communications, 2003, 1152–1153.

24. “Extended terpyridyl and triazine complexes of d6-metal centres,” C Metcalfe, S Spey, H Adams, JA Thomas
Journal of the Chemical Society, Dalton Trans., 2002, 4732–4739,

23. “Hetero-metallomacrocyclic hosts that bind molecular guests in water,” P de Wolf, S Heath, J Thomas
Chemical Communications, 2002, 2540-2541.

22. “A facile synthetic route to bimetallic ReI complexes containing two dppz DNA intercalating ligands,” C Metcalfe, M Webb, JA Thomas
Chemical Communications, 2002, 2026-2027.

21. “RuII Electron Transfer Systems Containing S-donor Ligands,” CS Araújo, MGB Drew, V Félix, L Jack, J Madureira, M Newell, S Roche, TM Santos, JA Thomas, L Yellowlees
Inorganic Chemistry, 2002, 41, 2250.

20. “Building Blocks for Self-Assembly: Half-Sandwich complexes of the [Ru([9]aneS3)]2+ Metal Center,” S Roche, SE Spey, H Adams, JA Thomas
Inorganica Chimica Acta 2001, 323, 157,

19. “Deprotonation of a ruthenium (II) complex incorporating a bipyrazole ligand leading to optical and electrochemical switching,” H Jones, M Newell, C Metcalfe, SE Spey, H Adams, JA Thomas
Inorganic Chemistry Communications, 2001, 4, 475.

18. “Blast it,” J. A. Thomas
New Scientist, 2000, 167, 2250, 40.

17. “Atomic abacus,”.J. A. Thomas
New Scientist, 2000, 165, 2225, 40.

16. “Controlling Substitution Chemistry in Ruthenium (II) Systems - Synthesis of Heteroleptic Complexes Incorporating the [Ru([9]aneS3)]2+ metal center,” S. Roche, H. Adams, S. E. Spey
Inorganic Chemistry, 2000, 39, 2385.

15. “Hydrogen-bond recognition of Cyclic Dipeptides in water,” C. Allot, H. Adams, P.L. Bernard Jr, C. Rotger, C.A. Hunter,  J. A. Thomas
Chemical Communications, 1998, 2449.

14. “Gripping Chemistry,” J. A. Thomas
New Scientist, 1998, 160, 2163, 36.

13. “Damage Control,”
New Scientist, 1998, 157, 2120, 36.

12. “Self-assembly of a Supramolecular Cube,” S. Roche, C. Haslam, H. Adams, S. L. Heath, J. A. Thomas
Chemical Communications, 1998, 1681.

11. “A highly coupled RuIII/RuII system incorporating sulphur donor ligands,” S. Roche, L. J. Yellowlees
Chemical Communications, 1998, 1429.

10. “Characterisation of two different mixed-valence states in a strongly interaction di-molybdenum complex,” A. Wlodarczyk, G. A. Doyle, J.P. Maher, J. A. Thomas,  C.J. Jones, J. McCleverty, M. D. Ward
Chemical Communications, 1997, 769.

9. “Stereoisomerically controlled architecture: synthesis of enantio- and diastereomerically pure tris-ruthenium discs from enantiopure building blocks,” K. Wärnmark, O. Heyke, J. A. Thomas,  J.-M. Lehn
Chemical Communications, 1996, 2603.

8. “Stereoisomerically controlled architecture: synthesis of enantio- and diastereomerically pure ruthenium-palladium molecular rods from enantiopure building blocks,” K. Wärnmark, J. A. Thomas, O. Heyke, J.-M. Lehn
Chemical Communications, 1996, 701.

7. “Mono- and bimetallic polypyridyl polyene cmplexes containing 17-electron molybdenum mononitrosyl centres,”  S. L. McWhinnie, J. A. Thomas, T. A. Hamor, C. J. Jones, J. A. McCleverty, D.Collison, F. E. Mabbs, C. J. Harding, L. J.Yellowlees, M. G. Hutchings
Inorganic Chemistry, 1996, 35, 760. .

6. “Solvatochromism of mono- and bidimolybdenum coordination complexes dipyridyloctatetraene,” J. A. Thomas, M. G. Hutchings, C. J. Jones, J. A. McCleverty
Inorganic Chemistry, 1996, 35, 289.

5. “Molecular Wires: An Electrochemical Study of metal-metal interactions through chains of four carbon atoms,” JA Thomas, CJ Jones, JA McCleverty, MG Hutchings
Polyhedron, 1996, 15, 1409-1414.

4. The synthesis and investigation of the electrochemical and mesogenic properties of metal organic complexes incorporating stilbazole ligands,” JA Thomas, CJ Jones, JA McCleverty, DW Bruce, MG Hutchings
Polyhedron, 1995, 14, 2499-2504.

3. “Electron exchange in bimetallic polyene bridged complexes,” JA Thomas, CJ Jones, JA McCleverty, T Hamor, CJHarding
Molecular Crystals and Liquid Crystals, 1993, 234, 103 -108

2. “Structure of Orthorhombic Triphenylphosphine Oxide,” JA Thomas, TA Hamor
Acta Crystallographica Section A, 1993, C49, 355.

1. “An EPR, magnetic and Electrochemical study of electron exchange and intermetallic interaction through polyene bridges,” J A Thomas, CJ Jones, JA McCleverty, TA Hamor, CJ Harding, MG Hutching
Journal of the Chemical Society, Chemical Communications, 1992, 1796.